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April 4, 2022

Crushing cholera

Promising results for new, longer-lasting vaccine

Cholera is a diarrheal illness caused by the highly transmissible bacteria V. cholerae which still infects two to three million people a year and kills tens of thousands annually. It is endemic in more than 50 countries. Oral vaccines on the market today last roughly two to five years and are not very effective in young children, a demographic particularly at risk of infection.

MSU chemist Xuefei Huang and Zahara Rashidijahanabad working in the Huang Group lab.
MSU chemist Xuefei Huang and then doctoral student Zahara Rashidijahanabad working in the Huang Group lab. Photo by Harley J. Seeley

In a paper recently published in the American Chemical Society journal Infectious Diseases, MSU chemist Xuefei Huang, former MSU doctoral student Zahra Rashidijahanabad and their international team announced promising test results for a new, longer-lasting cholera vaccine.

“ACS is one of the most trusted and read journals in our field,” said Rashidijahanabad, who now works at ThermoFisher Scientific. “I hope that this study will be reviewed by our peers and will lead to the development of more effective vaccines against cholera.”

Read more on the College of Natural Science's website.


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